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Test Code UIOD Iodine, 24 Hour, Urine

Reporting Name

Iodine, 24 Hr, U

Useful For

Assessing iodine toxicity or recent exposure in a 24-hour urine collection

 

Monitoring iodine excretion rate as index of replacement therapy

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Specimen Type

Urine


Necessary Information


24-Hour volume (in milliliters) is required.



Specimen Required


Patient Preparation:

1. High concentrations of gadolinium and iodine are known to interfere with most metal tests. If gadolinium- or iodine-containing contrast media has been administered, wait a minimum of 96 hours before starting collection.

2. If this test is used in conjunction with the (131)I uptake test, then specimen collection should begin immediately after the dose of (131)I is given (ie, the patient should void and discard urine just prior to the (131)I dose, and all subsequent urine should be collected for the next 24 hours). The last void should be included in the collection.

Supplies: Urine Tubes, 10 mL (T068)

Container/Tube: Plastic: 10-mL urine tube or clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 10 mL

Collection Instructions:

1. Collect urine for 24 hours.

2. Refrigerate specimen within 4 hours of completion of 24-hour collection.

3. See Trace Metals Analysis Specimen Collection and Transport for complete instructions.

Additional Information: See Urine Preservatives-Collection and Transportation for 24-Hour Urine Specimens for multiple collections.


Specimen Minimum Volume

0.3 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 146 days
  Ambient  146 days
  Frozen  146 days

Reference Values

0-17 years: Not established

≥18 years: 75-851 mcg/24 hour

Day(s) Performed

Tuesday, Friday

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

83789

Clinical Information

Iodine is an essential element for thyroid hormone production. The measurement of urinary iodine is preferred for assessment of toxicity, recent exposure, and monitoring iodine excretion rate as an index of replacement therapy.

Report Available

1 to 4 days

Reject Due To

  All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Method Name

Inductively Coupled Plasma Mass Spectrometry (ICP-MS)