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HelpTest Code OXAZS Oxazepam, Serum
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube: Red top (Serum gel/SST are not acceptable)
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Useful For
Assessing compliance
Monitoring for appropriate therapeutic level
Assessing oxazepam toxicity
Method Name
Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Oxazepam, SSpecimen Type
Serum RedSpecimen Minimum Volume
0.3 mL
Specimen Stability Information
| Specimen Type | Temperature | Time |
|---|---|---|
| Serum Red | Refrigerated (preferred) | 28 days |
| Ambient | 28 days | |
| Frozen | 28 days |
Reject Due To
| Gross hemolysis | OK |
| Gross lipemia | OK |
| Gross icterus | OK |
Clinical Information
Oxazepam is US Food and Drug Administration-approved for the management of anxiety disorders and is used to relieve anxiety, including that caused by alcohol withdrawal (symptoms may develop in people who stop drinking alcohol after drinking large amounts for an extended time). Oxazepam is in a class of medications called benzodiazepines. It works by slowing activity in the brain to allow for relaxation.
Oxazepam is metabolized by glucuronidation and has an intermediate half-life (approximately 4-16 hours) compared to other benzodiazepines. Common adverse effects include dizziness, headaches, somnolence and vertigo.
Reference Values
Therapeutic concentrations
Oxazepam: 200-1500 ng/mL
Cutoff concentrations by liquid chromatography tandem mass spectrometry:
Oxazepam: 10 ng/mL
Day(s) Performed
Monday, Wednesday
Report Available
3 to 7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
80299