Test Code FPOLO Poliovirus (Types 1, 3) Antibodies, Neutralization
Specimen Required
Specimen Type: Serum
Container/Tube: Red or SST
Specimen Volume: 1 mL
Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube(s) is acceptable. Spin down and send 1 mL of serum refrigerate in a plastic vial.
Method Name
Culture/Neutralization
Reporting Name
Poliovirus (Types 1, 3) Ab, NeutSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Serum | Refrigerated (preferred) | 14 days | |
Frozen | 30 days | ||
Ambient | 5 days |
Clinical Information
This sensitive procedure is recommended for vaccine response testing and type-specific serodiagnosis of recent poliovirus infection. It can also serve as an aid for diagnosing immune deficiency disorders.
Reference Values
Polio 1 Titer: <1:8
Polio 3 Titer: <1:8
The presence of neutralizing serum antibodies (titers 1:8 up to >1:128) against polioviruses implies lifelong immunity. Some persons without detectable titers (<1:8) may also be immune as demonstrated by elicitation of a secondary-type serum antibody response upon rechallenge with live polio vaccine.
Day(s) Performed
Monday and Thursday
Report Available
1 to 10 daysPerforming Laboratory
Quest DiagnosticsTest Classification
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.CPT Code Information
86382 x 2