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Test Code FPOLO Poliovirus (Types 1, 3) Antibodies, Neutralization


Specimen Required


Specimen Type: Serum

Container/Tube: Red or SST

Specimen Volume: 1 mL

 

Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube(s) is acceptable. Spin down and send 1 mL of serum refrigerate in a plastic vial.


Method Name

Culture/Neutralization

Reporting Name

Poliovirus (Types 1, 3) Ab, Neut

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  5 days

Clinical Information

This sensitive procedure is recommended for vaccine response testing and type-specific serodiagnosis of recent poliovirus infection. It can also serve as an aid for diagnosing immune deficiency disorders.

Reference Values

Polio 1 Titer:  <1:8

Polio 3 Titer:  <1:8

 

The presence of neutralizing serum antibodies (titers 1:8 up to >1:128) against polioviruses implies lifelong immunity. Some persons without detectable titers (<1:8) may also be immune as demonstrated by elicitation of a secondary-type serum antibody response upon rechallenge with live polio vaccine.

Day(s) Performed

Monday and Thursday

Report Available

1 to 10 days

Performing Laboratory

Quest Diagnostics

Test Classification

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

CPT Code Information

86382 x 2