Test Code FKEMS Ketamine and Metabolite Screen, Plasma
Specimen Required
***Must submit one specimen per order. Specimens cannot be shared between multiple orders.***
Specimen Type: Plasma
Collection Container/Tube: Lavender-top or pink top (EDTA)
Submission Container/Tube: Plastic vial
Specimen Volume: 3 mL
Collection Instructions:
1. Draw blood in an EDTA (lavender top or pink top) tube(s). Plasma gel tube is not acceptable.
2. Centrifuge and send 3 mL of plasma refrigerated in a preservative-free plastic vial.
Reflex Tests
Test ID | Reporting Name | Available Separately | Always Performed |
---|---|---|---|
FKETC | Ketamine and Metabolite Confirm, P | No | No |
Method Name
High Performance Liquid Chromatography/Tandem Mass Spectrometry (LC-MS/MS)
Reporting Name
Ketamine and Metabolite Screen, PSpecimen Type
Plasma EDTASpecimen Minimum Volume
0.9 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Plasma EDTA | Refrigerated (preferred) | 14 days | |
Frozen | 270 days | ||
Ambient | 14 days |
Reject Due To
Other | Polymer gel separation tube (SST or PST) |
Reference Values
Reporting limit determined each analysis
Units: ng/mL
Norketamine: None Detected
The intravenous administration of 2 mg/kg of Ketamine followed by continuous infusion of 41 mcg/kg/minute produced an average steady-state plasma concentration of 2200 ng Ketamine/mL and an average peak Norketamine level of 1050 ng/mL which occurred near the end of the 3 hour infusion.
Ketamine: None Detected
Reported levels during anesthesia: 500-6500 ng/mL
Performing Laboratory
NMS LabsTest Classification
This test was developed and its performance characteristics determined by NMS Labs. It has not been cleared or approved by the U.S. Food and Drug Administration.CPT Code Information
80307-Screen
80357-Confirmation, if appropriate
Day(s) Performed
Monday through Sunday