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Test Code FIGA Anti-IgA


Specimen Required


Specimen Type: Serum

Container/Tube: Red or SST

Specimen Volume: 1 mL

 

Collection Instructions: Draw blood in a plain, red-top tube(s) or serum gel tube(s). Spin down and send 1 mL of serum refrigerate in a plastic vial.


Method Name

Enzyme-Linked Immunosorbent Assay (ELISA)

Reporting Name

Anti-IgA

Specimen Type

Serum

Specimen Minimum Volume

0.5 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 7 days
  Frozen  30 days
  Ambient  7 days

Reject Due To

Hemolysis: NA
Thawing: Warm OK; Cold OK
Lipemia: NA
Icterus: NA
Other: NA

Clinical Information

For the evaluation of patients with recurrent infection for the possibility of IgA deficiency (IgAD). Patients with IgA deficiency may develop antibodies against IgA that make them susceptible to adverse reactions to blood products including intravenous immunoglobulin.

 

Reference Values

<99 U/mL

 

Patients with IgG antibodies against IgA may suffer from anaphylactoid reactions when given IVIG that contains small quantities of IgA. In one study (Clinical Immunology 2007; 122:156) five out of eight patients with IgG anti-IgA antibodies developed anaphylactoid reactions when IVIG was administered.

 

Day(s) Performed

Thursday

Report Available

5 to 16 days

Performing Laboratory

Eurofins Viracor

Test Classification

This test was developed and its performance characteristics determined by Viracor Eurofins. It has not been cleared or approved by the U.S. Food and Drug Administration.

CPT Code Information

83520