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HelpTest Code FAMDA Anti-MDA-5 Ab (CADM-140)
Ordering Guidance
This test is a component of the Myomarker 3 Profile and the Myomarker 3 Profile Plus.
Specimen Required
Collection Container/Tube: Red
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Acceptable: SST
Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube is acceptable. Spin down and send 1 mL of serum refrigerated in a plastic vial.
Method Name
Enzyme-linked immunosorbent assay (ELISA)
Reporting Name
Anti-MDA-5 Ab (CADM-140)Specimen Type
SerumSpecimen Minimum Volume
0.3 mL (volume does NOT allow for repeat testing)
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 60 days | ||
| Ambient | 7 days |
Reject Due To
| Gross hemolysis: | Reject |
| Thawing: | Warm OK; Cold OK |
| Gross lipemia: | Reject |
| Gross icterus | Reject |
| Other: | Anything other than serum; bacterial contamination |
Clinical Information
Anti-MDA5 antibodies are present in 7-35% of adult DM. Clinical features consist of absent or mild muscle symptoms (CADM), rapidly progressive ILD, specific mucocutaneous features of skin ulcerations and papules, oral ulcerations and arthritis.
Reference Values
Reference Range: <20
Interpretation:
Negative: <20 units
Weak Positive: 20-39 units
Moderate Positive: 40-80 units
Strong Positive: >80 units
Report Available
9 to 14 daysPerforming Laboratory
Esoterix EndocrinologyTest Classification
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.CPT Code Information
83520
Day(s) Performed
Sunday through Friday