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HelpTest Code FACN1 Anti-cN-1A (NT5c1A) IBM
Specimen Required
Collection Container/Tube: Red
Submission Container/Tube: Plastic vial
Specimen Volume: 2 mL
Acceptable: SST
Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube is acceptable. Spin down and send 2 mL of serum refrigerated in a plastic vial.
Method Name
Enzyme-linked immunosorbent assay (ELISA)
Reporting Name
Anti-cN-1A (NT5c1A) IBMSpecimen Type
SerumSpecimen Minimum Volume
0.5 mL (volume does NOT allow for repeat testing)
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 60 days | ||
| Ambient | 7 days |
Reject Due To
| Gross hemolysis: | Reject |
| Thawing: | Warm OK; Cold OK |
| Gross lipemia: | Reject |
| Gross icterus | Reject |
| Other: | Anything other than serum ; bacterial contamination |
Clinical Information
Anti-cN-1A autoantibodies in idiopathic inflammatory myopathy (IIM) patients appear to be disease-specific for sporadic Inclusion Body Myositis (sIBM) and are rarely detected in other autoimmune conditions. Anti-cN-1A autoantibodies have a moderate sensitivity, but their high specificity for sIBM may be helpful in the diagnosis of this infrequent and difficult-to-diagnose myopathy. This assay can augment and accelerate the suspected diagnosis of sIBM using sera where muscle biopsy is delayed and/or unfeasible.
Reference Values
Reference Range: <20
Interpretation:
Negative: <20 units
Weak Positive: 20 - 39 units
Moderate Positive: 40 - 80 units
Strong Positive: >80 units
Performing Laboratory
Esoterix EndocrinologyTest Classification
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.CPT Code Information
83516
Day(s) Performed
Varies; 1-2 days per week