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Test Code ABTIR Antibody Titer, Blood and Serum


Shipping Instructions


Specimen must arrive within 72 hours of collection.



Specimen Required


Blood cells, plasma, and serum are required.

 

Supplies: Sarstedt 5 mL Aliquot Tube (T914)

 

Specimen Type: Plasma/Blood

Collection Container/Tube: 6-mL Pink top(EDTA)

Submission Container/Tube: Plastic vial

Specimen Volume:

3 mL plasma

3 mL red blood cells (RBC)

Collection Instructions:

1. Centrifuge and aliquot plasma into plastic vial.

2. Label specimens as EDTA plasma or EDTA RBC, as appropriate.

3. Send both tubes.

 

Specimen Type: Serum/Blood

Collection Container/Tube: 10-mL Red top

Submission Container/Tube: Plastic vial

Specimen Volume:

5 mL serum

5 mL RBC

Collection Instructions:

1. Centrifuge and aliquot serum into plastic vial.

2. Label specimens as serum or clotted RBC, as appropriate.

3. Send both tubes.


Useful For

Monitoring antibody levels during pregnancy to help assess the risk of hemolytic disease of the newborn

 

This test is not useful for monitoring the efficacy of Rh-immune globulin administration.

Reflex Tests

Test ID Reporting Name Available Separately Always Performed
ABIDR Antibody Identification, RBC Yes No

Method Name

Hemagglutination

Reporting Name

Antibody Titer, RBC

Specimen Type

Varies

Specimen Minimum Volume

Blood: 6 mL EDTA
Pediatric: 2 mL serum

Specimen Stability Information

Specimen Type Temperature Time Special Container
Varies Ambient (preferred) 4 days
  Refrigerated  4 days

Reject Due To

No specimen should be rejected.

Clinical Information

Some maternal IgG alloantibodies to red blood cell antigens will cross the placenta and cause hemolysis of antigen-positive fetal red blood cells. The resulting fetal anemia and hyperbilirubinemia can be harmful or possibly fatal to the newborn.

Reference Values

Negative,

If positive, result will be reported as the reciprocal of the highest dilution at with macroscopic agglutination (1+) is observed.

Day(s) Performed

Monday through Friday, Sunday

Report Available

1 to 2 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

86886

86870 (if appropriate-per panel tested)

86860 (if appropriate)

86880 x 3 (if appropriate)

86905- (if appropriate)

86978 (if appropriate)

81403 (if appropriate)-Internal only