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Test Code 8INHT Factor VIII Inhibitor Profile, Technical Interpretation


Specimen Required


Only orderable as part of a profile. For more information see 8INHE / Factor VIII Inhibitor Evaluation, Plasma.


Useful For

Technical interpretation of inhibitor to factor VIII testing

 

This test is not useful for the detection of a lupus-like circulating anticoagulant inhibitor, a nonspecific circulating anticoagulant, or other inhibitors that are not specific for coagulation factors.

Disease States

  • Hemophilia A

Method Name

Only orderable as part of a profile. For more information see 8INHE / Factor VIII Inhibitor Evaluation, Plasma.

 

Technical Interpretation

Reporting Name

FVIII Inhib Profile Tech Interp

Specimen Type

Plasma Na Cit

Specimen Stability Information

Specimen Type Temperature Time Special Container
Plasma Na Cit Frozen 14 days

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Clinical Information

Factor VIII (FVIII) inhibitors are IgG antibodies directed against coagulation FVIII that typically result in development of potentially life-threatening hemorrhage. These antibodies may develop in 1 of 4 different patient populations:

-Patients with congenital FVIII deficiency (hemophilia A) in response to therapeutic infusions of factor VIII concentrate

-Older nonhemophiliac adult patients (not previously factor VIII deficient)

-Women in postpartum period

-Patients with other autoimmune illnesses

Reference Values

Only orderable as part of a profile. For more information see 8INHE / Factor VIII Inhibitor Evaluation, Plasma.

 

An interpretive report will be provided.

Day(s) Performed

Monday through Friday

Report Available

3 to 5 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

Not Applicable

CPT Code Information

85390