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Test Code PDEIS Phosphodiesterase 10A (PDE10A) IgG, Tissue Immunofluorescence, Serum


Specimen Required


Only orderable as part of a profile. For more information see:

ENS2 / Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum

DMS2 / Dementia, Autoimmune/Paraneoplastic Evaluation, Serum

EPS2 / Epilepsy, Autoimmune/Paraneoplastic Evaluation, Serum

MDS2 / Movement Disorder, Autoimmune/Paraneoplastic Evaluation, Serum


Useful For

Detecting phosphodiesterase 10A (PDE10A)-IgG in serum specimens

 

Evaluation of autoimmune/paraneoplastic neurological syndromes among patients presenting with movement disorders and encephalopathy

Method Name

Only orderable as part of a profile. For more information see:

ENS2 / Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum

DMS2 / Dementia, Autoimmune/Paraneoplastic Evaluation, Serum

EPS2 / Epilepsy, Autoimmune/Paraneoplastic Evaluation, Serum

MDS2 / Movement Disorder, Autoimmune/Paraneoplastic Evaluation, Serum

 

Indirect Immunofluorescence Assay (IFA)

Reporting Name

PDE10A Ab IFA, S

Specimen Type

Serum

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 28 days
  Frozen  28 days
  Ambient  72 hours

Reject Due To

Gross hemolysis Reject
Gross lipemia Reject
Gross icterus Reject

Clinical Information

Phosphodiesterase 10A (PDE10A) is a marker of paraneoplastic neurological autoimmunity in patients presenting with movement disorders, encephalopathy, and often, cancer.

Reference Values

Only orderable as part of a profile. For more information see:

ENS2 / Encephalopathy, Autoimmune/Paraneoplastic Evaluation, Serum

DMS2 / Dementia, Autoimmune/Paraneoplastic Evaluation, Serum

EPS2 / Epilepsy, Autoimmune/Paraneoplastic Evaluation, Serum

MDS2 / Movement Disorder, Autoimmune/Paraneoplastic Evaluation, Serum

 

Negative

Day(s) Performed

Monday through Sunday

Report Available

5 to 10 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.

CPT Code Information

86255