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Test Code CACR3 Calcium/Creatinine Ratio, Random, Urine


Specimen Required


Supplies: Sarstedt Aliquot Tube 5 mL (T914)

Collection Container/Tube: Clean, plastic urine container with no metal cap or glued insert

Submission Container/Tube: Plastic, 5-mL tube or a clean, plastic aliquot container with no metal cap or glued insert

Specimen Volume: 4 mL

Collection Instructions:

1. Collect a random urine specimen.

2. No preservative.


Useful For

Evaluation of calcium oxalate and calcium phosphate kidney stone risk

 

Calculation of urinary supersaturation

 

Evaluation of bone diseases, including osteoporosis and osteomalacia

Profile Information

Test ID Reporting Name Available Separately Always Performed
CCTR Calcium/Creat Ratio, Random, U No Yes
CALC5 Calcium, Random, U No Yes
CRETR Creatinine, Random, U No Yes

Method Name

CALC5: Photometric

CRETR: Enzymatic Colorimetric Assay

Reporting Name

Calcium/Creat Ratio, Random, U

Specimen Type

Urine

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  30 days
  Ambient  72 hours

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Clinical Information

Calcium is the fifth most common element in the body. It is a fundamental element necessary to form electrical gradients across membranes, an essential cofactor for many enzymes, and the main constituent in bone. Under normal physiologic conditions, the concentration of calcium in serum and in cells is tightly controlled. Calcium is excreted in both urine and feces. Ordinarily about 20% to 25% of dietary calcium is absorbed, and 98% of filtered calcium is reabsorbed in the kidney. Traffic of calcium between the gastrointestinal tract, bone, and kidney is tightly controlled by a complex regulatory system that includes vitamin D and parathyroid hormone. Sufficient bioavailable calcium is essential for bone health. Excessive excretion of calcium in the urine is a common contributor to kidney stone risk.

Reference Values

1 month-<12 months: 0.03-0.81 mg/mg creatinine

12 months-<24 months: 0.03-0.56 mg/mg creatinine

24 months-<3 years: 0.02-0.50 mg/mg creatinine

3 years-<5 years: 0.02-0.41 mg/mg creatinine

5 years-<7 years: 0.01-0.30 mg/mg creatinine

7 years-<10 years: 0.01-0.25 mg/mg creatinine

10 years-<18 years: 0.01-0.24 mg/mg creatinine

18 years-83 years: 0.05-0.27 mg/mg creatinine

Reference values have not been established for patients who are less than 1 month of age.

Reference values have not been established for patients who are greater than 83 years of age.

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.

CPT Code Information

82310

82570

Day(s) Performed

Monday through Sunday

Report Available

1 to 3 days

Forms

If not ordering electronically, complete, print, and send a Renal Diagnostics Test Request (T830) with the specimen.