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HelpTest Code FFRFT Anti-Synthetase Profile
Specimen Required
Collection Container/Tube: 10 mL Red
Submission Container/Tube: Plastic vial
Specimen Volume: 3 mL
Acceptable: SST
Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube is acceptable. Spin down and send 3 mL of serum refrigerated in a plastic vial.
Method Name
RIPA Gel Radiography; ELISA
Reporting Name
Anti-Synthetase ProfileSpecimen Type
SerumSpecimen Minimum Volume
1 mL (volume does NOT allow for repeat testing)
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 14 days | |
| Frozen | 60 days | ||
| Ambient | 7 days |
Reject Due To
| Gross hemolysis: | Reject |
| Thawing: | Warm OK; Cold OK |
| Gross lipemia: | Reject |
| Gross icterus | Reject |
| Other: | Anything other than serum; bacterial contamination |
Clinical Information
This Anti-Synthetase Profile is comprised of Anti-Jo-1 Ab, Anti-PL-7 Ab, Anti-PL-12 Ab, Anti-EJ Ab and Anti-OJ Ab. Anti-synthetase syndrome is an autoimmune disease characterized by interstitial lung disease (ILD), non-erosive arthritis, myositis, Raynaud’s phenomenon, unexplained fever and/or mechanic’s hands.
Reference Values
Anti-PL-7 Ab, Anti-PL-12 Ab, Anti-EJ Ab, Anti-OJ Ab:
Reference Range: Negative
Interpretation for:
Anti-Jo-1 Ab:
Reference Range: <20
Negative: <20 units
Weak Positive: 20-39 units
Moderate Positive: 40-80 units
Strong Positive: >80 units
Day(s) Performed
Monday through Friday
Report Available
16 to 25 daysPerforming Laboratory
Esoterix EndocrinologyTest Classification
This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.CPT Code Information
83516 x 4
86235