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Test Code FAT1G Anti-TIF-1gamma Antibody


Specimen Required


Collection Container/Tube: Red

Submission Container/Tube: Plastic vial

Specimen Volume: 1 mL

Acceptable: SST

Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube is acceptable. Spin down and send 1 mL of serum refrigerated in a plastic vial.


Method Name

Enzyme-linked immunosorbent assay (ELISA)

Reporting Name

Anti-TIF-1gamma Ab

Specimen Type

Serum

Specimen Minimum Volume

0.3 mL (volume does NOT allow for repeat testing)

Specimen Stability Information

Specimen Type Temperature Time Special Container
Serum Refrigerated (preferred) 14 days
  Frozen  60 days
  Ambient  7 days

Reject Due To

Gross hemolysis: Reject
Thawing: Warm OK; Cold OK
Gross lipemia: Reject
Gross icterus Reject
Other: Anything other than serum; bacterial contamination

Clinical Information

Anti-TIF-1(P155) antibodies are present in 15-38% of adult DM and 20-30% in JDM. Highly associated with malignancy which is found in 50-75% of positive adult patients; 89% specificity and 78% sensitivity for diagnosing cancer associated DM; no cancer association in children.

Reference Values

Reference Range: <20

 

Interpretation:

Negative: <20 units

Weak Positive: 20 - 39 units

Moderate Positive: 40 - 80 units

Strong Positive: >80 units

Performing Laboratory

Esoterix Endocrinology

Test Classification

This test was developed and its performance characteristics determined by LabCorp. It has not been cleared or approved by the Food and Drug Administration.

CPT Code Information

86235

Day(s) Performed

Monday through Friday

Report Available

9 to 14 days