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HelpTest Code TICKS Tick-Borne Disease Antibodies Panel, Serum
Reporting Name
Tick-Borne Ab Panel, SUseful For
Evaluation of the most common tick-borne diseases found in the United States, including Lyme disease, human monocytic and granulocytic ehrlichiosis, and babesiosis
Evaluation of patients with a history of, or suspected, tick exposure who are presenting with fever, myalgia, headache, nausea, and other nonspecific symptoms
Seroepidemiological surveys of the prevalence of the infection in certain populations
Profile Information
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| EHRC | Ehrlichia Chaffeensis (HME) Ab, IgG | Yes | Yes |
| ANAP | Anaplasma phagocytophilum Ab, IgG,S | Yes | Yes |
| BABG | Babesia microti IgG Ab, S | Yes | Yes |
| LYME | Lyme Disease Serology, S | Yes | Yes |
Reflex Tests
| Test ID | Reporting Name | Available Separately | Always Performed |
|---|---|---|---|
| LYWB | Lyme Disease Ab, Immunoblot, S | Yes | No |
Performing Laboratory
Mayo Clinic Laboratories in Rochester
Specimen Type
SerumOrdering Guidance
During the acute phase of an Anaplasma phagocytophilum, Ehrlichia chaffeensis or Babesia infection, serologic tests are often nonreactive; polymerase chain reaction (PCR) testing is available to aid in the diagnosis of these cases; see TIKLB / Tick-Borne Panel, Molecular Detection, PCR, Blood.
Specimen Required
Supplies: Sarstedt Aliquot Tube, 5 mL (T914)
Collection Container/Tube:
Preferred: Serum gel
Acceptable: Red top
Submission Container/Tube: Plastic vial
Specimen Volume: 1 mL
Collection Instructions: Centrifuge and aliquot serum into a plastic vial.
Specimen Minimum Volume
See Specimen Required
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Serum | Refrigerated (preferred) | 10 days | |
| Frozen | 14 days |
Reference Values
Ehrlichia chaffeensis (HME) ANTIBODY, IgG
<1:64
Reference values apply to all ages.
Anaplasma phagocytophilum ANTIBODY, IgG
<1:64
Reference values apply to all ages.
Babesia microti IgG ANTIBODIES
<1:64
Reference values apply to all ages.
LYME DISEASE SEROLOGY
Negative
Reference values apply to all ages.
Day(s) Performed
Monday through Friday
CPT Code Information
86618
86666 x 2
86753
86617 x 2-Lyme disease Western blot (if appropriate)
Special Instructions
Clinical Information
In North America, ticks are the primary vectors of infectious diseases.(1) Worldwide, ticks rank second only to mosquitoes in disease transmission. In the United States, tickborne diseases include Lyme disease, Rocky Mountain spotted fever, human monocytic and granulocytic ehrlichiosis, babesiosis, tularemia, relapsing fever, and Colorado tick fever.
Symptoms of the various tick-vectored diseases range from mild to life-threatening and significantly overlap. Early symptoms, which include fever, aches, and malaise, do not aid in distinguishing the various diseases. Because early treatment can minimize or eliminate the risk of severe disease, early detection is essential, yet patients may not have developed distinctive symptoms to help in the differential diagnosis. A tickborne panel can assist in identifying the pathogen, allowing treatment to be initiated.
For information on the specific diseases, see the individual test IDs.
Report Available
2 to 4 daysReject Due To
| Gross hemolysis | Reject |
| Gross lipemia | Reject |
| Gross icterus | Reject |
| Heat-inactivated specimen | Reject |
Method Name
EHRC, ANAP, BABG: Immunofluorescence Assay (IFA)
LYME: Enzyme-Linked Immunosorbent Assay (ELISA)
Forms
If not ordering electronically, complete, print, and send Infectious Disease Serology Test Request (T916) with the specimen.