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Test Code RAT11 Oxalate/Creatinine Ratio, Urine


Specimen Required


Only orderable as part of a profile. For more information see ROXUR / Oxalate, Random, Urine.


Useful For

Calculating the oxalate concentration per creatinine

Method Name

Only orderable as part of a profile. For more information see ROXUR / Oxalate, Random, Urine.

 

Calculation

Reporting Name

Oxalate/Creatinine Ratio

Specimen Type

Urine

Specimen Minimum Volume

1 mL

Specimen Stability Information

Specimen Type Temperature Time Special Container
Urine Refrigerated (preferred) 14 days
  Frozen  14 days
  Ambient  72 hours

Reject Due To

All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.

Clinical Information

Oxalate is an end product of glyoxalate and glycerate metabolism. Humans have no enzyme capable of degrading oxalate so it must be eliminated by the kidney.

 

In tubular fluid, oxalate can combine with calcium to form calcium oxalate stones. In addition, high concentrations of oxalate may be toxic for renal cells.

 

Increased urinary oxalate excretion results from inherited enzyme deficiencies (primary hyperoxaluria), gastrointestinal disorders associated with fat malabsorption (secondary hyperoxaluria), or increased oral intake of oxalate-rich foods or vitamin C.

 

Since increased urinary oxalate excretion promotes calcium oxalate stone formation, various strategies are employed to lower oxalate excretion.

Reference Values

Only orderable as part of a profile. For more information see ROXUR / Oxalate, Random, Urine.

 

No established reference values.

Day(s) Performed

Monday through Saturday

Report Available

3 days

Performing Laboratory

Mayo Clinic Laboratories in Rochester

Test Classification

Not Applicable