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HelpTest Code FHI24 Histamine, 24-Hour Urine
Specimen Required
Patient Preparation: Avoid direct sunlight. Patient should refrain from taking allergy causing drugs, antihistamines, oral corticosteroids, and substances which block H2 receptors for at least 24 hours prior to specimen collection.
Specimen Type: Urine
Submission Container/Tube: Plastic, 10-mL tube (T068)
Specimen Volume: 4 mL
Collection Instructions:
1. Collect urine for 24 hours, with 10 mL 6N HCL preservative.
2. Avoid direct sunlight during the 24-hour collection.
3. Send specimen refrigerated in the plastic, 10-mL urine tube (T068).
4. Collection volume and duration are required.
Method Name
Immunoassay (IA)
Reporting Name
Histamine, 24-Hour USpecimen Type
UrineSpecimen Minimum Volume
2 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Urine | Refrigerated (preferred) | 14 days | |
| Frozen | 14 days | ||
| Ambient | 48 hours |
Reject Due To
| Thawing** | Warm < 48 hours OK; Cold OK |
| List other reasons for rejection | Random Urine |
Clinical Information
Histamine is a mediator of the allergic response. Histamine release causes itching, flushing, hives, vomiting, syncope, and even shock. In addition, some patients with gastric carcinoids may exhibit high concentrations of histamine.
Reference Values
0.006-0.131 mg/24 h
Day(s) Performed
Tuesday, Friday
Report Available
5 to 11 daysPerforming Laboratory
Quest Diagnostics Nichols InstituteTest Classification
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics Nichols Institute, San Juan Capistrano. This test should not be used for diagnosis without confirmation by other medically established means.CPT Code Information
83088