Test Code CRT24 Creatinine, 24 Hour, Urine
Specimen Required
Only orderable as part of a profile. For more information see:
-NMH24 / N-Methylhistamine, 24 Hour, Urine
-RB24 / Retinol-Binding Protein, 24 Hour, Urine
-A124 / Alpha-1-Microglobulin, 24 Hour, Urine
Useful For
Urinary creatinine, in conjunction with serum creatinine, is used to calculate the creatinine clearance, a measure of renal function
Normalizing urinary analytes to account for the variation in urinary concentration
Method Name
Only orderable as part of a profile. For more information see:
-NMH24 / N-Methylhistamine, 24 Hour, Urine
-RB24 / Retinol-Binding Protein, 24 Hour, Urine
-A124 / Alpha-1-Microglobulin, 24 Hour, Urine
Enzymatic Colorimetric Assay
Reporting Name
Creatinine, 24 HR, USpecimen Type
UrineSpecimen Minimum Volume
1 mL
Specimen Stability Information
Specimen Type | Temperature | Time | Special Container |
---|---|---|---|
Urine | Refrigerated (preferred) | 30 days | |
Frozen | 30 days | ||
Ambient | 14 days |
Reject Due To
All specimens will be evaluated at Mayo Clinic Laboratories for test suitability.Clinical Information
Creatinine is formed from the metabolism of creatine and phosphocreatine, both of which are principally found in muscle. Thus, the amount of creatinine produced is in large part dependent upon the individual's muscle mass and tends not to fluctuate much from day-to-day.
Creatinine is not protein-bound and is freely filtered by glomeruli. All of the filtered creatinine is excreted in the urine.
Renal tubular secretion of creatinine also contributes to a small proportion of excreted creatinine. Although most excreted creatinine is derived from an individual's muscle, dietary protein intake, particularly of cooked meat, can contribute to urinary creatinine levels.
The renal clearance of creatinine provides an estimate of glomerular filtration rate.
Reference Values
Only orderable as part of a profile. For more information see:
-NMH24 / N-Methylhistamine, 24 Hour, Urine
-RB24 / Retinol-Binding Protein, 24 Hour, Urine
-A124 / Alpha-1-Microglobulin, 24 Hour, Urine
Normal values mg per 24 hours:
Males: 930-2955 mg/24 hours
Females: 603-1783 mg/24 hours
Reference values have not been established for patients who are less than 18 years of age.
For SI unit Reference Values, see https://www.mayocliniclabs.com/order-tests/si-unit-conversion.html
Performing Laboratory
Mayo Clinic Laboratories in RochesterTest Classification
This test has been cleared, approved, or is exempt by the US Food and Drug Administration and is used per manufacturer's instructions. Performance characteristics were verified by Mayo Clinic in a manner consistent with CLIA requirements.Day(s) Performed
Monday through Sunday